2215 Systemic activation of the VEGF receptor KDR/FLK-1 leads to angiogenesis
نویسندگان
چکیده
SYSTEMIC ACTIVATION OF THE VEGF RECEPTOR KDWFLK-1 LEADS TO ANGIOGENESIS. FAVARD C.1, ORTEGA N.2, POULIQUEN Y.‘., RUCHOUX M-h@, and PLOUET J.2 1 Hotel Dieu, Paris, (France) 2 LBME CNRS, Toulouse, (France) 3Hopital B, Lille, (France) PurDose, Vascular endothelial growth factor (VEGF) stimulates retinal capillary endothelial cell proliferation through the activation of its receptor KDR. To investigate the role of VEGF in the onset of neovascularization we designed circulating agonists of KDR and looked at their angiogenic potential. Method. Anti-VEGF idiotypic antibodies were elicited in
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عنوان ژورنال:
- Vision Research
دوره 35 شماره
صفحات -
تاریخ انتشار 1995